UNIT II: PROSTEREOISOMERISM AND CONFORMATIONAL STUDY

UNIT II: PROSTEREOISOMERISM AND CONFORMATIONAL STUDY 15 hrs.

Topicity and Prostereoisomerism: topicity of ligands and faces – homotopic ligands and faces 

– enanatiotopic ligands and faces – diastereotopic ligands and faces – nomenclature of 

stereoheterotopic ligands and faces – symbols for stereoheterotopic ligands and faces –

prostereoisomerism and stereoisomerism – chemical and biochemical transformation of 

stereoheterotopic ligands and faces – molecules with one prochiral center – Re and Si system 

of nomenclature for ligands.

Conformations of cyclic systems – conformation of monosubstituted cyclohexanes –

disubstituted cyclohexanes: typical – atypical disubstituted cyclohexanes – conformation of 

polysubstituted cyclohexanes – conformation of fused bicyclic ring systems: decalins –

conformational study of fused polycyclic ring systems: perhydrophenanthrenes –

perhydroanthracenes – structure and nomenclature of bridged ring systems.